Azimuth-dependentEslayer instability: A missing link found

Chronic Inflammation and Premenstrual Syndrome: A Missing Link Found?

Premenstrual symptoms are highly prevalent among women of reproductive age. Population-based studies suggest as much as 85%–90% of women regularly experience one or more physical, emotional, or behavioral symptoms before the onset of menses. For the majority of women, symptoms are relatively mild and do not adversely impact quality of life. For 15%–20% of women, symptoms are severe enough to im...

Chromosome Segregation: A Kinetochore Missing Link Is Found

During mitosis the kinetochore assembles on centromeric chromatin. The component that connects the chromatin-associated inner domain to the microtubule-binding outer domain has eluded researchers. Two new studies identify a conserved molecular linkage between the inner and outer kinetochore.

Cytoskeleton: Missing links found?

The quest for the function of BPAG1, a major hemidesmosomal protein of skin keratinocytes, has led to the discovery of a group of protein isoforms derived from the same genomic locus that are involved in organizing and integrating cytoskeletal networks in sensory neurons.

Embryonic PCNA: a missing link?

PCNA, the processivity factor of the eukaryotic replicative DNA polymerase [1], is the functional homolpgue of the [3 subunit of Escherichia coli DNA polymerase III holo-enzyme [2,3]. Biochemical studies have shown that the E. coli 3 subunit acts as a sliding clamp on duplex DNA; it has a ring shape that encircles DNA and it binds directly to Pol III, tethering it to DNA to achieve highly proce...

loving and humane care: a missing link in nursing